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CJC-1295 no DAC is a synthetic GHRH (growth hormone-releasing hormone) analog that can be used for the purpose of enhancing and increasing an animal's GH release. However, there is no DAC to this compound (as with DAC drugs such as Bremelanotide). This means MGF will have a short duration in the body and will not be long lasting.
It is a 29 amino acid peptide that mimics the natural GHRH(Growth Hormone Releasing Hormone), with any Amino Acid supplied, as this is a versatile Growth Hormone variant. Scientists use it to investigate how it works in the body, its possible benefits and how it may help with muscle growth, recovery and hormonal changes as we age.
Peptide Sequence (IUPAC Condensed): H-DL-Tyr-DL-Ala-DL-Asp-DL-Ala-DL-xiIle-DL-Phe-DL-xiThr-DL-Gln-DL-Ser-DL-Tyr-DL-Arg-DL-Lys-DL-Val-DL-Leu-DL-Ala-DL-Gln-DL-Leu-DL-Ser-DL-Ala-DL-Arg-DL-Lys-DL-Leu-DL-Leu-DL-Gln-DL-Asp-DL-xiIle-DL-Leu-DL-Ser-DL-Arg-NH2
Molecular Formula: C152H252N44O42
Molecular Weight: 3367.9 g/mol
Synonyms: Modified GRF 1-29, Mod GRF 1-29, CJC-1295 without DAC
View the CJC-1295 no DAC Certificate Of Analysis (COA)
View the CJC-1295 no DAC High Performance Liquid Chromatography (HPLC)
All our peptides are guaranteed a purity of +99%. Third party lab testing is available upon request.
CJC-1295 no DAC works by stimulating the body’s own growth hormone releasing hormone, or GHRH. It does this by binding to GHRH receptors in the anterior pituitary, which activates a pathway called cAMP, or cyclic adenosine monophosphate. Therefore, it promotes the secretion of growth hormone (GH) from the pituitary in a manner consistent with the body’s normal time of GH release.
No-DAC versionThe no-DAC version of CJC-1295 has a short half-life causing it to stay active for only some days, giving the actions of stimulating growth hormone (GH) release sometimes short activities. It is being studied for its relationship to the somatotropic axis and how it may affect one's growth, recovery, and metabolism.
Purchase CJC-1295 No DAC peptide vial online for laboratory research purposes at https://peptide-works.com/cjc-1295-no-dac/. This lyophilized peptide is 99 percent pure and is available in vials of 2, 5, and 10 mg or as a kit where bacteriostatic water and syringes are included for reconstitution.
Elevated GH and IGF-1: mod GRF 1-29 temporarily promotes growth hormone release by acting on the pituitary gland, causing pulsatile elevations in GH levels which then cause subsequent IGF-1 increases. GHRH gene ablation and human consumption studies confirmed that these clinical trials dose-dependently increased and sustained IGF-1 levels without suppression of growth hormone synthesis. These results underscore the possibility of its use in protection and/or promoting muscle strength, helping to maintain normal body weight, and exercise optimal peptide hormone function.
Better Body Composition and Weight Loss: This peptide heightens natural growth hormone production that increases IGF-1 levels. Such a pulsatile pattern of release may contribute to muscle building, maintenance of lean body mass and fat reduction.
Animal studies, particularly in GHRH-knockout mice, demonstrated improved body composition (increased lean mass and decreased fat mass) following treatment. This effect is sometimes amplified by more frequent dosing. Although human data is meager, the evidence suggests that increasing GH-IGF-1 actions can favorably affect muscle mass and reduce both visceral and subcutaneous fat.
Improved Sleep: Studies show that modified GRF improves GH and IGF-1 levels, which may be related to regulating sleep. Studies demonstrate that GH deficiency is linked with a higher intensity of slow-wave sleep (SWS) which probably results from hyperactivity of the hypothalamic GHRH.
GH replacement treatment as with CJC-1295 could normalize this through lowering the overly high SWS intensity and improving sleep quality where this is an issue. The long-acting nature of CJC may be beneficial to sleep regulation; however, direct effects of CJC on sleep need further evaluation.
Improved Memory: CJC-1295 no DAC has the potential to support improved brain health with GH and IGF-1 levels, which are important for proper brain functioning, per research. Research demonstrates that GHRH treatment enhances executive function and verbal memory in cognitively intact older adults and individuals suffering from mild cognitive impairment (MCI).
Further, GH has neuroprotective properties and it contributes to recovery in stroke models by enhancing spatial memory and neuronal repair. These results indicate that CJC-1295 may improve brain functioning and have the potential to mitigate age-related decline in brain function and neurodegenerative diseases.
Cardioprotective: Research has indicated that GRF 1-29 has cardioprotective effects on the heart without action on the GH/IGF-1 axis by inducing cardiac repair. Jingui Shenqi Wan is also used to treat coronary heart disease and inflammation, while animal studies have demonstrated that GHRH agonists such as JI-38 could ameliorate cardiac function, remodelling, and anti-apoptotic gene expression following myocardial infarction (MI).
In contrast to IGF-1 that regulates inflammation, leading to anti-inflammatory macrophages, GHRH agonists increase proliferation of cardiac precursor cells and their healing as such providing a potential therapeutic pathway for the recovery from heart damage.
Wound Healing and Muscle Repair: Studies have shown that CJC-1295 no DAC can contribute to wound healing as well as muscle repair, both of which are direct results of GH production. IGF-1 stimulates keratinocyte migration, wound re-epithelialization and the synthesis of hyaluronan which helps in difficult-to-heal wounds like burns and diabetic ulcers.
GH also stimulates collagen deposition, angiogenesis, and granulation tissue formation but inhibits inflammation as observed in intestinal healing models. The net effect just described would contribute to its potential in the acceleration of tissue repair.
Purchase CJC-1295 no DAC Pre-Mixed Pen Online for Research Studies In vitro CJC 1295 noDAC is considered as a powerful growth hormone releasing hormone (GHRH) mimetic which stimulates the release of growth hormones in pulse. Both available are the products in single cartridges and also as a pen kit: Pen Kit (Injection Pen, 1 single use needle tips, 1 cartridge with CJC-1295 no DAC pre-mixed with bacteriostatic water)Individual cartridges.
CJC-1295 no DAC FAQs What is the CJC-1295 peptide?
Purchase CJC-1295 No DAC Peptide Nasal Spray from PeptideWorks.com for Research. Available in 15 ml and 30 ml glass spray bottles, this non-invasive option offers a straightforward and convenient delivery method for research purposes.
How Often Should CJC-1295 no DAC be Injected & What Schedule?
CJC-1295 No DAC has a short half-life and its branches are usually prepared for several times a day in order to achieve effective release. Frequent hourly time intervals are used in dosing. Cycles are typically for a few weeks to be followed by an off period before resuming in order to support consistent, controlled and measurable results.
What are the side effects of CJC-1295 no DAC?
Side effects if occur, might include a sudden mild redness at the site of injection, transient water retention and small changes in energy or hunger. These reactions may or may not be independent of peptide purity, concentration, and handling. Good preparation and storage can decrease unwanted variability in response.
Can you Stack CJC-1295 no DAC with Other Peptides?
Another favourite of researchers is the CJC-1295 no DAC combined with Ipamorelin. Increasing growth hormone secretagogue receptor effects of ipamorelin peptide stack in the body, it results in a slower pulse release of GH. Clinical studies and research done by entities like the International IGF Research Society demonstrate this in terms of sustaining a good nitrogen balance, stimulating urea cycle enzymes and promoting conformational changes in pituitary RNA. Precise preparation and timing are essential to ensure reliable results in controlled experiments, most especially when it comes to the consumption by animals and advanced research with growth hormone.
Is there a safe and legal place to purchase CJC-1295 no DAC USA?
Cjc-1295 no dac for sale Peptide has not been approved by FDA (United States Food and Drug Administration) for human or animal consumption.
Can I purchase CJC-1295 no DAC in bulk or large amounts?
Can you buy cjc-1295 no dac in bulk? Contact our customer service team for negotiations of a bulk discount.
IS CJC SAFE FOR USE COMPARED TO HGH PEPTIDES?
This article discusses the safety variances in CJC1295 and HGH peptides in research related laboratories. It underscores CJC-1295’s support of the natural growth hormone pulsatility, receptor suppression, and blood sugar effects.
Is CJC-1295 Without DAC Safer?
In this post, we take a closer look at the advantages and safety of using CJC-1295 no DAC, a short half-life GH secretagogue. It does not have the DAC chain attached to it. It is essentially a cycle on its own, so unlike tren that “builds up”.
Advantages of Combining Ipamorelin with CJC-1295
This blog explores the formation and synergistic properties of Ipamorelin, and CJC-1295. It reveals why and how these two ingredients are interconnected in a way that encourages the release of growth hormone, which could affect muscle recovery, fat metabolism, sleep quality and physical signs of aging.
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DISCLAIMER: Our products are Not for human consumption All products we provide (including these books) are research chemicals, and are not for human consumption. This categorization permits their use only for research development and laboratory experiments. The content on our Peptide Works website: https://peptide-works.com/ is for educational use only. These items are not intended for human or animal use, consumption or application. These items should only be handled by appropriately trained personnel. They shall not be considered a drug, food, cosmetic or curative and should not be permanently misbranded or used as such.
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